domenica 31 agosto 2008

IBIOCAT JUNIOR ZONE: A tour around the amazing world of jazz (NOT ONLY FOR KIDS!!)

Click here if you want to start an unforgettable tour around the amazing world of jazz music:
 
 
Have fun!
 
 
Laura Cipollina - IBIOCAT, Divisione Marketing e Commerciale
 
 
 
 

IBIOCAT Musical Entertainment: A tour around the amazing world of Jazz

Jazz has been called the purest expression of American democracy; a music built on individualism and compromise, indipendence and cooperation. Click here for an eploration of jazz, America's greatest cultural achievement.
 
In the videoclip available at http://www.pbs.org/jazz/about/jazz56.html jazz musicians and writers describe in poetic terms the unbreakable bond between the spirit of jazz and the spirit of America.
 
And now...five ways to say "Round Midnight" :
 
1) Oscar Peterson:
 
2)  Thelonius Monk Quartet: 
 
3)  Miles Davis Quintet:
 
4)  Michael Brecker:
 
5)  Bobby McFerrin:
 
I hope you'll enjoy my music choice!
 
 
Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale
 
 
 
 

Green Thought for Today August 31, 2008

"If only one idea had to be passed to the next generation,
it is the concept of Atoms and Molecules, and that everything
is made of them".
 
 
Richard P. Feynman
 
 
Richard Phillips Feynman (May 11, 1918 – February 15, 1988) was an American physicist known for the path integral formulation of quantum mechanics, the theory of quantum electrodynamics, the physics of the superfluidity of supercooled liquid helium, as well as work in particle physics (the parton model was proposed by him). For his contributions to the development of quantum electrodynamics, Feynman was a joint recipient of the Nobel Prize in Physics in 1965, together with Julian Schwinger and Sin-Itiro Tomonaga. Feynman developed a widely-used pictorial representation scheme for the mathematical expressions governing the behavior of subatomic particles, which later became known as Feynman diagrams. He assisted in the development of the atomic bomb and was a member of the panel that investigated the Space Shuttle Challenger disaster. In addition to his work in theoretical physics, Feynman has been credited with pioneering the field of quantum computing, and introducing the concept of nanotechnology (creation of devices at the molecular scale). He held the Richard Chace Tolman professorship in theoretical physics at Caltech. Richard Feynman's interest in biology was more than casual. He was a friend of Esther Lederberg, the geneticist and microbiologist who developed replica plating and discovered bacteriophage lambda (though often others received credit for her work). It is not surprising that both these engaging people should be friends, as they also shared other scientists as friends. These included physicists in nuclear research who for moral reasons switched to genetics (such as Leó Szilárd, Guido Pontecorvo, Aaron Novick, and Carl Sagan).

 

(Source: Wikipedia)

 

 

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

giovedì 28 agosto 2008

IBIOCAT Humor- A musical parody for you: "The brain chemicals"

"The Brain Chemicals"
sung to the tune of Old MacDonald Had a Farm  ("Nella vecchia fattoria" for Italy)
Lyrics by Julie Jeppesen, Sean J. Weinberg, Rhonda Waggoner, Marcie E. Ball, Beth Cowman, Sharon LeaTrea - all Illinois teachers

 

Acetylcholine in my brain
         B-R-A-I-N
Acetylcholine in my brain
        B-R-A-I-N
It's most abundant -- aids in memory and thought
abundant, abundant, memory and thought
Acetylcholine in my brain
       B-R-A-I-N

 

Norepinephrine in my brain
      B-R-A-I-N
Norepinephrine in my brain
      B-R-A-I-N
Short term to long term - improves mood
short term, long term improves mood
Norepinephrine in my brain
     B-R-A-I-N

 

Dopamine is in my brain
    B-R-A-I-N
Dopamine is in my brain
   B-R-A-I-N
Physical movement, improves mood
Physical movement, improves mood
Dopamine is in my brain
  B-R-A-I-N

 

Serotonin in my brain
    B-R-A-I-N
Serotonin in my brain
    B-R-A-I-N
smooth muscle movement - improves mood
smooth muscle movement - improves mood
Serotonin in my brain
   B-R-A-I-N

 

There is GABA in my brain
     B-R-A-I-N
There is GABA in my brain
    B-R-A-I-N
Keeps us calm; neurons don't fire at once
Keeps us calm; neurons don't fire at once
There is GABA in my brain
   B-R-A-I-N

 

Endorphins are in my brain
   B-R-A-I-N
Endorphins are in my brain
   B-R-A-I-N
Makes one feel good; helps one concentrate
feels good - concentrate
feels good - concentrate
Endorphins are in my brain
   B-R-A-I-N

 

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

 

 

martedì 26 agosto 2008

COOL SITE August 27, 2008 - "The Delights of Chemistry "

Cool site: August 27, 2008  http://www.chem.leeds.ac.uk/delights/ 
 
Enjoy the 

Delights of Chemistry

from Department of Chemistry, University of Leeds, UK

"Chemistry lies right at the heart of all science. Chemistry controls the way our bodies work, it controls our atmosphere and environment and is the driving force for much that is successful in British industry today. Chemistry impacts on all aspects of our lives."

Professor Philip Kocienski, Head of Chemistry, University of Leeds. 

 

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

THE IBIOCAT'S BOOK CORNER- Biocatalysis and Bioenergy

Biocatalysis and Bioenergy
Publisher: Wiley-Interscience
ISBN: 978-0-470-13404-7
Hardcover
608 pages
September 2008
£78.95 / €100.00
This price is valid for Italy
 
 
 
An up-to-date overview of diverse findings and accomplishments in biocatalysis and bioenergy.
With the high price of petroleum and researchers worldwide seeking new means of producing energy, this comprehensive book on biocatalysis for bioenergy and biofuel applications is very timely. It combines information on state-of-the-art advances and in-depth reviews of the latest achievements in biocatalysis and bioenergy, emphasizing biodiesel, bioethanol, and industrial products. The advantages of biocatalysis include high specificity, efficiency, energy conservation, and pollution reduction. Biocatalysis and Bioenergy details advances in the field, with:
Three primary sections, covering biodiesel research, bioethanol, and industrial products;
Information on enzyme catalysis, biotransformation, bioconversion, fermentation, genetic engineering, and product recovery;
Contributions from leading experts worldwide who share their research and findings.

The prospect of using biocatalysis for the production of energy has great potential due to its cost-effectiveness, the fact that it does not require a limited resource such as oil, and its potential universality of application and use globally. This is the definitive reference for biochemists and biochemical engineers, bioprocess and bioenergy scientists, physical and oil chemists (oleochemists), microbiologists, industrial microbiologists, molecular biologists, metabolic engineers working in biocatalysis, bioethanol, and biodiesel fuels, DOE scientists working on renewable energy, and other professionals in related fields. 
 
For further information visit the Publisher's website
 
View here the  TABLE OF CONTENTS 
 
 
 
Laura Cipollina - IBIOCAT, Divisione Marketing e Commerciale

sabato 23 agosto 2008

IBIOCAT Humor - A musical parody for you: "Metabolise" by Aimee Hartnell

METABOLISE
 
To be sung to  the tune of  "I Will Survive"
Original Words and Music by Dino Fekaris and Freddie Perrin

 
"Two pyruvates are made from glycolysis:
First glucose gains phosphate from ATP hydrolysis
Then it's isomerised, and then turned into fructose bisphosphate
Which then relates
To two 3C carbohydrates
Each gains phosphate (with phosphorylase),
They're oxidised by NAD+ (with a dehydrogenase)
And in the last three steps they're made into pyruvate, finally,
And there's a net gain of two molecules of lovely ATP…

It's aerobic respiration
(Not as efficient - but more controlled than combustion)
It's got to get all twelve hydrogens oxidised,
To turn six carbons into six carbon dioxides;
To oxidise! Metabolise!
Oh it starts off in the cytosol, where sugar's glycolysed
The TCA cycle goes on
In a mitochondrion
Metabolise - metabolise…!!

(musical bit)

Pyruvate loses CO2 (forms NADH)
Its ethanoyl group forms acetyl coenzyme A
4C oxaloacetate joins on to make 6C citrate,
Eight steps go round;
And two more CO2 are found;
One ATP each cycle gains,
Reduced coenzymes make more in the electron transport chain:
Four from two FADH2, ten NADH - and each yields three:
Altogether from one glucose that's 38 ATP

It's aerobic respiration
(Not as efficient - but more controlled than combustion)
It's got to get all twelve hydrogens oxidised,
To turn six carbons into six carbon dioxides;
To oxidise! Metabolise!
Oh it starts off in the cytosol, where sugar's glycolysed
The TCA cycle goes on
In a mitochondrion
Metabolise - metabolise….!!! "

(repeat till bored...!)
 
 
Aimee Hartnell, April 2000

 
Gloria Gaynor sings "I will survive":  
 
 
Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

venerdì 22 agosto 2008

Biocatalysis in the News - "Microwave Activation of Enzymatic Catalysis"

US Researchers Discover Novel Method for Activating Enzymatic Reactions

Researchers at North Carolina State University have discovered a new method for "switching on" enzymatic reactions with precise energy delivery, by using microwave radiation. Dr. Alex Deiters, assistant professor of chemistry, and Dr. Bob Kelly, Alcoa Professor of Chemical and Biomolecular Engineering, along with other NC State researchers, found that hyperthermophilic enzymes - proteins that thrive in extremely hot environments - could be activated at temperatures far below those normally required for biocatalysis, the process by which enzymes chemically transform organic compounds. Their findings appear in the online edition of the Journal of the American Chemical Society.The use of enzymes as "biocatalysts" is nothing new - biocatalysis is important in everything from brewing beer to the creation of pharmaceutical components. Applying heat to the enzymes causes them to activate a chemical reaction; however, when temperatures become too high, the proteins can become "denatured," and the reaction can produce undesirable by-products. The researchers theorized that the unique properties of the hyperthermophiles and the use of microwave radiation as a heat source might help them avoid this pitfall."Using microwaves means that you are only heating up what you want to heat up," says Kelly. "You're focusing the energy much more specifically and rapidly, and the process can occur at a much lower temperature". Hyperthermophilic enzymes are particularly well-suited to the process, because they are less likely to denature when exposed to the rapid heating from the microwave radiation.The results bore out the researchers' expectations: the hyperthermophilic enzymes were activated when irradiated by microwaves, and at a much lower temperature than would normally be required to cause the reaction."The microwaves will allow us to be much more precise in our ability to induce these reactions, and to stop them quickly before denaturing occurs" Deiters says. "This is another tool we can use to maximize the utility of biocatalysis."Future work will show if using microwave radiation to activate enzymes below their typical reaction temperature will create energy-saving benefits for researchers using biocatalytic processes.

An abstract of the paper follows:

Douglas D. Young, Jason Nichols, Robert Kelly, and Alexander Deiters, "Microwave Activation of Enzymatic Catalysis". J. Am. Chem. Soc., 2008; 130 (31): 1004810049.
Abstract: Microwave irradiation can be used to regulate biocatalysis. Herein, the utilization of hyperthermophilic enzymes in a microwave reactor is reported. While these enzymes are inactive at low temperatures, they can be activated with microwave irradiation. To the best of our knowledge, this is the first illustration of a specific microwave effect in enzymatic catalysis.
Web Release Date: July 10, 2008.

Laura Cipollina -IBIOCAT, Divisione Marketing e Commerciale

giovedì 21 agosto 2008

Green Thought for Today August 21, 2008

"Science cannot solve the ultimate mystery of nature. And that is because, in the last analysis, we ourselves are a part of the mystery that we are trying to solve"

Max Planck

Karl Ernst Ludwig Marx Planck, better known as Max (Kiel, April 23, 1858Göttingen, October 4, 1947), was a German physicist. Although being a very gifted musician (he took singing lessons and played piano, organ and cello, and composed songs and operas), he chose to study physics and is now often considered to be the founder of quantum theory for which he won the Nobel Prize in Physics in 1918. Several years after studying at the University of Munich, he became a professor at Berlin University where he developed his ideas and established a new professorship for Albert Einstein. The two scientists became friends and met frequently to play music.

Read more about Max Planck's: http://en.wikipedia.org/wiki/Max_Planck

 

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

 

mercoledì 20 agosto 2008

Save the date! September 7-10, 2008 - ESBES 7- 7th European Symposium on Biochemical Engineering Science - Faro, Portugal

The 7th European Symposium on Biochemical Engineering Science will take place in the beautiful town of Faro at the Algarve Coastline in Portugal from 7 - 10 September, 2008. The symposium is jointly organised by the IBB Institute of Biotechnology and Bioengineering, the University of Algarve, and DECHEMA, Frankfurt.
The ESBES Symposium Series has developed to the leading platform for the community over the last years which provides the opportunity for biochemical scientists and engineers but also for researchers of adjacent fields to exchange their experiences.
Topics: Bioreaction Engineering, Biocatalysis and Biotransformation, Bioseparation; M3C Modelling, Monitoring, Measurement & Control; Solid State Bioprocession; Biomedical and Tissue Engineering; Engineering Challenges for Biotechnology Industry; Biofuel Engineering and Sustainability; Miniaturisation in Bioengineering and Nanobiotechnology; Biothermodynamics.
 
For detailed information please visit http://www.esbes2008.org/

Download the Scientific programme

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale


 

martedì 19 agosto 2008

Biocatalysis in the News - Researchers Create Safer Alternative to Heparin

Larger amounts of fully synthetic heparin could be ready for use in patients in five years

Robert Linhardt has spent years stitching together minuscule carbohydrates to build a more pure and safer alternative to the commonly used and controversial blood thinner heparin. At the national conference of the American Chemical Society on August 17, 2008, Linhardt announced that his research team may have accomplished this task by building the first fully synthetic heparin. Their creation is the largest dose of heparin ever created in the lab. Linhardt, who is the Ann and John H. Broadbent Jr. '59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering at Rensselaer Polytechnic Institute (located in Troy New York), was on the international team that identified the suspected contaminant in the Chinese heparin, a structurally similar carbohydrate called oversulfated chondroitin sulfate. "When we found the contamination, it was another sign that the way we currently manufacture heparin is simply unsafe," he said. "Unlike the current heparin that is harvested from possibly disease carrying animals in often very poor conditions, our fully synthetic heparin will be created in a pharmaceutical manufacturing environment from fermentation to packaging. This will give drug manufacturers extreme control over the safety and purity of the product."The carbohydrate backbone for the new heparin comes from the bacteria E. coli. The use of the common and easily grown bacteria makes this version of heparin much easier and faster to produce, according to Linhardt. The team used a process called chemoenzymatic synthesis that used specialized synthetic chemicals and natural enzymes expressed in E. coli to replicate the normal biosynthesis of natural heparin within the cell.The dose that Linhardt and his team were able to produce with this method was a million times higher than any other alternative created to date. He will now continue to work with his partners to take the milligram dose that they have developed and expand it to kilograms. "Ultimately, drug companies are going to need to produce tons of this drug to keep up with global demand," he said. "Such levels of productions are further down the road. We think that in five years, it is very possible that this drug could reach human clinical trials." The milligram-scale synthesis of heparin will be published in the Journal of the American Chemical Society.

Read more: http://news.rpi.edu/update.do?artcenterkey=2480

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

 

lunedì 18 agosto 2008

IBIOCAT Junior Zone - "The Atoms Family", a creation by Kathleen Crawford (1994)

"In the center of Matterville, there is a place called  the Nucleus Arcade, where two members of the Atoms Family like to hang out. Perky Patty Proton, like her sisters, is quite large with a huge smile and eyes that sparkle (+). Patty is always happy and has a very positive personality. Nerdy Nelda Neutron is large like Patty, but she has a boring, flat mouth and eyes with zero expression (o). Her family is very apathetic and neutral about everything. Patty, Nelda, and their sisters spend all their time at the arcade. Around the Nucleus Arcade, you will find a series of roadways that are used by another member of the Atoms Family, Enraged Elliott Electron. Elliott races madly around the Arcade on his bright red chromeplated Harley-Davidson. He rides so fast that no one can be sure where he is at any time. Elliott is much smaller than Patty and Nelda and he is always angry because these bigger relatives will not let him in the Arcade. He has a frown on his face, eyes that are squinted with anger, and a very negative (-) attitude.

Do you like this story? Read it in full:

http://sciencespot.net/Media/atomsfam.pdf

Enjoy!

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

 
 

martedì 12 agosto 2008

FESTIVAL DELLA MENTE 2008 (Va Edizione) - Il primo festival europeo dedicato alla creatività- Sarzana (La Spezia), 29-30-31 agosto 2008

Dopo il successo dello scorso anno con 31mila presenze, il Festival della Mente, ideato e diretto da Giulia Cogoli, giunge alla quinta edizione, chiamando a raccolta una cinquantina tra scrittori, artisti, musicisti, architetti, antropologi, storici, registi, attori, oltre a scienziati e filosofi italiani e stranieri, che presenteranno un intervento, una performance, una lectio o un workshop nuovo e originale, legato al tema della creatività.
Il programma della quinta edizione prevede oltre 60 appuntamenti di cui 22 laboratori per bambini e ragazzi.
Ritorna, dopo il sorprendente successo di pubblico dello scorso anno, la sezione approfonditaMente, una serie di incontri-lezioni-laboratori sui temi del design, religione, ambiente, cucina, poesia, retorica, e arte, della durata di circa due ore e mezzo, per un numero limitato di persone, così che si possa creare un rapporto più stretto e efficace tra pubblico e relatore.

I protagonisti della quinta edizione:
gli storici dell'arte Giovanni Agosti e Francesco Poli; il regista Roberto Andò; il fotografo Ferdinando Scianna; gli antropologi Marc Augé, Marco Aime e Franco La Cecla; le psicoanaliste Simona Argentieri e Silvia Vegetti Finzi; il magistrato Giuseppe Ayala; il giornalista inglese Misha Glenny; il neuroscienziato Bruno G. Bara; la divulgatrice scientifica Sylvie Coyaud; lo chef Carlo Cracco; il poeta Maurizio Cucchi; il biblista Paolo De Benedetti; gli storici Carlo Ginzburg e Alessandro Barbero; l'enigmista Stefano Bartezzaghi; il giornalista enogastronomico Allan Bay; i filosofi Remo Bodei, Armando Massarenti, Vito Mancuso, Laura Boella, Salvatore Natoli; lo scienziato Edoardo Boncinelli, la grecista Eva Cantarella; il critico e giornalista culturale Antonio Gnoli; lo scrittore e giornalista Carlo Grande; gli architetti Emiliano Armani e Andrew Todd; l'etologo Danilo Mainardi; il logico Matteo Motterlini; lo scrittore Giulio Mozzi; il matematico Piergiorgio Odifreddi; l'attore, regista e scrittore Moni Ovadia; lo storico del design Vanni Pasca Raymondi; lo scrittore e storico della letteratura Walter Siti; il violoncellista e compositore Giovanni Sollima; il pianista e compositore Cesare Picco; il giardiniere e scrittore Umberto Pasti; l'editor e traduttore Davide Tortorella; lo scrittore Vittorio Sermonti; l'attore e regista Toni Servillo.

E ancora, per i più piccoli: Fabia Bellese con Editoriale Scienza; lo stilista Stephan Janson; Chiara Mainetti con Fondazione Mondadori; Matefitness; Cittàdellarte Fondazione Pistoletto con Associazionedidee; l'illustratore Alessandro Sanna; l'artista Marta Dell'Angelo con la studiosa di neuroestetica Ludovica Lumer.

 
Scarica il programma completo in PDF: http://www.festivaldellamente.it/pdf/programma2008.pdf
 
 
Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale

THE IBIOCAT’S BOOK CORNER- Enzyme Biocatalysis: Principles and Applications

Enzyme Biocatalysis

Principles and Applications

Illanes, Andrés (Ed.)

Springer Netherlands,  2008, X, 398 p., Hardcover

ISBN: 978-1-4020-8360-0

124,95 €, $189.00, SFr. 207.50, £94.00

 

 

 

"The book is intended to provide a sound basis for enzyme reactor design based on kinetic principles, and give an updated vision of the potentials and limitations of enzyme biocatalysis, especially with respect to recent applications in processes of organic synthesis. The book is structured in the form of a textbook that goes from basic principles of enzyme structure and function to reactor design for homogeneous systems with soluble enzymes, and heterogeneous systems with insolubilized enzymes. It contains an introductory chapter that gives an updated overview of enzyme technology, a chapter on enzyme production focused on large-scale operations, two chapters devoted to homogeneous and heterogeneous enzyme kinetics and a chapter on enzyme reactor design and operation based on enzyme kinetics principles, mass transfer limitations and enzyme inactivation. The book is complemented with case studies of biocatalytic processes of industrial relevance or potential, written by experts in those fields. Applications of proteases, acylases, lipases, aldolases and dehydrogenases in reactions of organic synthesis, and peroxidases in the degradation of recalcitrant organic compounds, are used as selected examples to illustrate the realities and potentials of enzymes as process catalysts.

Written for:

Researchers and students in biochemistry, biotechnology, genetic engineering; an excellent book for those working in the field of enzyme technology"

 

 

Please note that this information is taken from:  

http://www.springer.com/chemistry/biotech/book/978-1-4020-8360-0

 

 

Laura Cipollina-IBIOCAT, Divisione Marketing e Commerciale

domenica 10 agosto 2008

IBIOCAT Musical Entertainment - August 10, 2008

(L'uomo che dentro di sè non ha la musica,
che l'armonia dei suoni non commuove,
è incline al tradimento, al furto, alla perfidia;
buia come la notte è la sua intelligenza,
oscuro come l'Erebo è il suo pensiero.
Diffida di quest'uomo. Ascolta la musica).
 
William Shakespeare. The Merchant of Venice (V, i, 83-88)
 
 
Selected for you: 
 
Gustav Mahler, 1860-1911. Adagietto from Symphony No. 5 in C sharp minor. Zubin Mehta Conductor

Completed 1902, first performance October 18, 1904 at Köln (Cologne). The complete symphony is scored for a large orchestra, but the Adagietto is scored for harp and strings only. "Surely the most beautiful music the composer ever set to paper, it serves as perhaps the supreme example of Mahler's mastery of orchestration. Most of the orchestra is idled, but rather than choosing a conventional string ensemble, he adds a single harp to provide an underpinning of motion to the lazily soaring melody. This simple change is pure genius, producing a sonority that has never been matched before or since. Closing the eyes and relaxing in the concert hall, one can easily imagine a peaceful sunset in the mountains the composer loved, bringing a perfect end to the day's solitude and the last true happiness he would know" (Geoff Kuenning, 1994).

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale
 

venerdì 8 agosto 2008

IBIOCAT Science&Art - RALFONSO "Dance With The Wind"- Kinetic sculpture for Olympic Park Beijing, China 2008

Ralfonso Gschwend (1959), who shares his time between his native Switzerland and Florida, employs air currents, light and water in his impressive kinetic sculpture. "Dance with the Wind" is the nine foot tall working prototype he created for the 30-foot sculpture version that was commissioned for this summer's 2008 Olympic Park in Beijing, China. A striking illustration of compound pendulums, this dynamic work is composed of stacked spheres in decreasing diameter, each swaying within a dimensional perimeter that pivots independently, suggesting an oversized and unhinged shimmering necklace. Reminiscent of the exquisitely polished experiential public sculpture of Anish Kapoor, this sculpture uses the reflection of its environment to pull the viewer in, while the rhythmic oscillations conjure chaos. Ralfonso was invited and selected as one of twenty international artists to create a sculpture for Olympic Park. The small version (9') working-prototype was installed in Geneva, Switzerland in April, 2008
 
A short movie of how sculpture moves in the wind:
http://www.youtube.com/watch?v=KDtvdl3-hD4 

Learn more about Ralfonso's kinetic sculptures:

~ Select among 15 movies at:
http://www.youtube.com/results?search_query=ralfonso

~ See a comprehensive overview about Ralfonso on Wikipedia at:
http://en.wikipedia.org/wiki/Ralfonso_Gschwend

~ Ralfonso is also President of the international Kinetic Art Organization (KAO) 
http://www.kinetic-art.org

~ Check-out Ralfonso's website to view many more of his creations at:
http://www.ralfonso.com

(Information taken from http://www.asci.org/artikel988.html)

 

Laura Cipollina- IBIOCAT, Divisione Marketing e Commerciale